TENSARIN TABLET

TENSARIN is an effective herbal remedy for anxiety, depression, high blood pressure and insomnia.

Contents: Nardostachys grandiflora (Root), Rauwolfia serpentia (Root), Acorus calamus (Rhizome), Elaeocarpus ganitrus (Seed), Withania somnifera (Rhizome),Tinospora cordifolia (Stem)

Action : Combination has antihypertensive, sedative and anxiolytic properties which helps in lowering blood pressure and palpitation.

Indication : Anxiety, hypertension and insomnia.

Doses & administration : Adult : 1 tablet twice a day to be adjusted according to patient condition. Children : 1 tablet daily. To be taken orally with water.

Presentation : Bottle of 60 and 120 tablets.

Research article:

Evaluation of anxiolytic activity of tensarin in mice.

Rauniar GP, Deo S, Bhattacharya SK.

Source

Department of Pharmacology, BP Koirala Institute of Health Sciences, Ghopa, Dharan, Nepal. gprauniar@hotmail.com

Abstract

INTRODUCTION:

Anxiolytic drugs are amongst the most frequently prescribed drugs. Available anxiolytic agents are associated with several limitations. Several indigenous drugs are being evaluated but none has been proved to be effective.

OBJECTIVES:

Aim of the present study is to evaluate the anxiolytic effect of Tensarin.

MATERIAL AND METHOD:

The behavioural tests were conducted with single dose schedule and multiple seven-dose schedules of Tensarin 50mg/kg, 100mg/kg and 200mg/kg in comparison with Diazepam 1mg/kg in mice using open field test, activity-monitoring and passive avoidance test. There were eight treatment groups in each treatment schedule. Each group consisted of ten animals of either sex. The data obtained were analyzed using non- parametric test and P-value of less than 0.05 was considered to be statistically significant.

RESULTS:

Multiple doses produced anxiolytic effect as indicated by an increase in rearing, number of crossing and the time spent by the animals in Central Square. It was also seen that there was significant decrease in step down latency, increase in step down error and time spent by animal in shock zone, these effects were not observed in single dose study.

CONCLUSION:

Tensarin shows a dose dependent anxiolytic effect but further studies are needed to find out the exact mechanism of action of the formulation.

PMID:

18604017

[PubMed – indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

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LinkOut – more resources

http://www.kumj.com.np/issue/18/188-194.pdf